Levobupivacaine shortage — BE supply status & alternatives

Levobupivacaine

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🇦🇺 AUST R 76815 · Abbvie Pty Ltd

In supply · Australia

In supply · 🇦🇺 Australia · short in🇧🇪 BE🇮🇪 IE🇳🇱 NL

In supply in Australia

Reading today’s signals…

✓ Can I substitute?

In supply

no shortage substitution needed

⇄ Best alternative

None listed

refer to prescriber

◷ Expected back

No estimate

No estimate provided

Product attributes reference data we hold

Active ingredient (INN)	Levobupivacaine
Therapeutic category	Auto-created by CBG-MEB (Netherlands) scraper
Controlled substance	No

Marketing-authorisation holders	ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI SPA, FRESENIUS KABI LIMITED, Abbvie Pty Ltd

Registrations on file	11

Patient information leaflet (PIL)	Not on file

Summary of product characteristics (SPC)	Not on file

Trade price 🇦🇺 Australia · awaiting price ingest

🇦🇺 AU

Ex-manufacturer

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Dispensed (DPMQ)

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Pack

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Not yet captured for Australia

Official pricing isn’t on file for this market yet. PBS (Australia), NHS Drug Tariff (United Kingdom) and CMS NADAC (United States) feeds are prioritised; this panel populates automatically once the data lands.

Global API supply base 🇺🇸 FDA Drug Master Files · active Type II

1 API manufacturer

Manufacturers with an active Type II Drug Master File — i.e. cleared to supply this active ingredient into the US market. A proxy for how concentrated the global manufacturing base is.

Very high concentration risk

Edmond Pharma Srl

Manufacturing countries: Italy · Source: FDA List of Drug Master Files

Registration recordmarketing-authorisation holders

Registrations & marketing-authorisation holders11 registrations · 3 MA holders

Product	Strength	Form	Market	MA holder	Status
LEVOBUPIVACAINE 2.5 MG/ML SOLUTION FOR INJECTION/INFUSION	2.5 MG	injection	🇬🇧 GB	ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI SPA	Active
LEVOBUPIVACAINE 5 MG/ML SOLUTION FOR INJECTION/INFUSION	5 MG	injection	🇬🇧 GB	ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI SPA	Active
LEVOBUPIVACAINE 7.5 MG/ML SOLUTION FOR INJECTION/INFUSION	7.5 MG	injection	🇬🇧 GB	ISTITUTO BIOCHIMICO ITALIANO GIOVANNI LORENZINI SPA	Active
LEVOBUPIVACAINE 0.625 MG/ML SOLUTION FOR INFUSION	0.625 MG	solution	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
LEVOBUPIVACAINE 1.25 MG/ML SOLUTION FOR INFUSION	1.25 MG	solution	🇬🇧 GB	FRESENIUS KABI LIMITED	Active
CHIROCAINE levobupivacaine	25mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active
CHIROCAINE levobupivacaine	50mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active
CHIROCAINE levobupivacaine	75mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active
CHIROCAINE levobupivacaine hydrochloride	62.5mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active
CHIROCAINE levobupivacaine hydrochloride	125mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active
CHIROCAINE levobupivacaine hydrochloride	250mg	—	🇦🇺 AU	Abbvie Pty Ltd	Active

For health-professional reference only. Mederti aggregates shortage and substitution information from official regulatory sources. It is not clinical advice and data may be incomplete or delayed. Confirm any substitution or supply decision against the primary regulator source, the prescriber, and current clinical references (e.g. AMH) before acting. Terms.