Pyrimethamine shortage — GR supply status & alternatives

Pyrimethamine

—

🇦🇺 AUST R 97456

In supply · Australia

In supply · 🇦🇺 Australia · short in🇬🇷 GR

In supply in Australia

Reading today’s signals…

✓ Can I substitute?

In supply

no shortage substitution needed

⇄ Best alternative

None listed

refer to prescriber

◷ Expected back

No estimate

No estimate provided

Product attributes reference data we hold

Active ingredient (INN)	Pyrimethamine
Therapeutic category	Auto-created by FDA Drug Enforcement — Full Recall Database scraper
Controlled substance	No
Marketing-authorisation holders	TEVA PHARMACEUTICALS, INC.

Registrations on file	2

Patient information leaflet (PIL)	Not on file

Summary of product characteristics (SPC)	Not on file

Trade price 🇦🇺 Australia · awaiting price ingest

🇦🇺 AU

Ex-manufacturer

—

Dispensed (DPMQ)

—

Pack

—

Not yet captured for Australia

Official pricing isn’t on file for this market yet. PBS (Australia), NHS Drug Tariff (United Kingdom) and CMS NADAC (United States) feeds are prioritised; this panel populates automatically once the data lands.

Other markets

🇺🇸 US

US$137.01

Acquisition

Substitution pathways 🇦🇺 Australia · TGA

—

No substitution instrument in force

Dispense per normal rules, or refer to the prescriber. No active SSSI/S19A instrument detected for this medicine.

How long have past shortages lasted? from 1 resolved event

◷

~0 month

Historical pattern from resolved shortage records — not a prediction of this event.

Global API supply base 🇺🇸 FDA Drug Master Files · active Type II

8 API manufacturers

Manufacturers with an active Type II Drug Master File — i.e. cleared to supply this active ingredient into the US market. A proxy for how concentrated the global manufacturing base is.

Low concentration risk✓ 3 WHO-prequalified

Apitoria Pharma Private LTDMangalam Drugs and Organics LtdGuilin Pharmaceutical Co LtdAnuh Pharma Ltd.Fukuzyu Pharmaceutical CO LTDIpca Laboratories LTD+2 more

Manufacturing countries: India, China, Japan · Source: FDA List of Drug Master Files

FDA-approved products 🇺🇸 Drugs@FDA

Approved applications

Generic (ANDA)

Brand (NDA/BLA)

Aug 2021

Latest approval

Shortage status by regulator official notices

🇬🇷

EOF · 2d ago

Medium

Recalls official enforcement reports

🇺🇸

Pyrimethamine

Health Innovations Pharmacy, Inc · Feb 2015

Class IIdetails ↗

Verified timeline regulator events

🇬🇷 4 May 2026

Shortage resolved

🇬🇷 2 Feb 2026

medium reported

Sources official regulators

🇬🇷

EOF

verified 2d ago

verify ↗

Registration recordmarketing-authorisation holders

Registrations & marketing-authorisation holders2 registrations · 1 MA holder

Product	Strength	Form	Market	MA holder	Status
DARAPRIM pyrimethamine	25mg	tabuc	🇦🇺 AU	—	Active
Pyrimethamine	25mg/1	tablet	🇺🇸 US	TEVA PHARMACEUTICALS, INC.	Active

Mederti Drug Report

Generated 3 July 2026 · Australia market · 1 regulatory source

For health-professional reference only. Mederti aggregates shortage and substitution information from official regulatory sources. It is not clinical advice and data may be incomplete or delayed. Confirm any substitution or supply decision against the primary regulator source, the prescriber, and current clinical references (e.g. AMH) before acting. Terms.